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Sculpt Nation by V Shred Test Boost Max Capsules
-1%
Sculpt Nation

Sculpt Nation by V Shred Test Boost Max Capsules

Rs 22,700Rs 23,000
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MaxLife Naturals DIM+SGS Hormone Balance Support Capsules
-2%
MaxLife Naturals

MaxLife Naturals DIM+SGS Hormone Balance Support Capsules

Rs 12,700Rs 13,000
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Enhanced Labs Top T 18 in 1 Premium Testosterone Booster for Men 120 Capsules
-33%
Enhanced

Enhanced Labs Top T 18 in 1 Premium Testosterone Booster for Men 120 Capsules

Rs 10,000Rs 15,000
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Nutricost Black Cohosh For Women 660 Mg Capsules
-26%
Nutricost

Nutricost Black Cohosh For Women 660 Mg Capsules

Rs 7,000Rs 9,500
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Nutricost Women DIM With Calcium D-Glucarate Dong Quai Capsules
-17%
Nutricost

Nutricost Women DIM With Calcium D-Glucarate Dong Quai Capsules

Rs 10,000Rs 12,000
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Laperva Dim Complex & Bioperine Capsules
-6%
Laperva

Laperva Dim Complex & Bioperine Capsules

Rs 6,600Rs 7,000
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Biaxol PCT Post Cycle Therapy
-8%
Biaxol

Biaxol PCT Post Cycle Therapy

Rs 6,000Rs 6,500
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Deep dive

About DIM

Everything you need to know about this ingredient — sourced from our editorial team and the brands we work with.

About this ingredient

DIM (Diindolylmethane), also known as 3,3′-Diindolylmethane, is a naturally occurring phytochemical formed from indole-3-carbinol (I3C), a compound found in cruciferous vegetables such as broccoli, cabbage, Brussels sprouts and cauliflower.

DIM is best known for its research involving estrogen metabolism and hormone-related pathways. Human studies have shown that DIM supplementation can alter urinary estrogen-metabolite profiles, but these biochemical changes should not automatically be interpreted as improved clinical outcomes.

DIM has also been investigated in breast, cervical, prostate and other hormone-related research. However, clinical evidence remains limited, and DIM should not be marketed as a cancer-prevention or cancer-treatment product. Memorial Sloan Kettering notes that human data are still limited.

An important consideration is that DIM can influence drug-metabolizing pathways. In a randomized trial involving women taking tamoxifen, DIM changed estrogen metabolism but also reduced circulating tamoxifen metabolites, including endoxifen, highlighting a potentially important drug interaction.

Health benefits

  • ✓🌿 Provides a cruciferous-vegetable-derived phytochemical
  • ✓🧬 Supports research into estrogen metabolism
  • ✓⚖️ Supports hormonal-health formulations
  • ✓🔬 Supports research into hormone-related cellular pathways
  • ✓🥦 Provides a compound derived from indole-3-carbinol
  • ✓🛡️ Supports phytochemical and antioxidant research
  • ✓👩 Supports women's wellness formulations
  • ✓👨 Supports men's hormonal-health research
  • ✓🧪 Supports nutritional and biochemical research
  • ✓🌱 Supports botanical wellness formulations

Common uses

  1. 1💊 DIM capsules
  2. 2💊 DIM tablets
  3. 3🌿 DIM botanical supplements
  4. 4👩 Women's wellness formulations
  5. 5⚖️ Hormonal-health supplements
  6. 6🧬 Estrogen-metabolism research
  7. 7🔬 Phytochemical research
  8. 8🥦 Cruciferous-vegetable phytochemical formulations
  9. 9👨 Men's wellness formulations
  10. 10🧪 Nutritional research products
Got questions?

Frequently asked questions

What is DIM?

DIM stands for Diindolylmethane, a phytochemical formed from indole-3-carbinol found in cruciferous vegetables.

What is DIM used for?

DIM is primarily used in nutritional supplements focused on hormonal wellness and estrogen-metabolism research.

Does DIM affect estrogen metabolism?

Yes. Human studies have demonstrated that DIM can change urinary estrogen-metabolite profiles. However, changing a biomarker does not necessarily mean that DIM improves a particular health outcome.

Is DIM a natural compound?

DIM occurs as a metabolite of compounds from cruciferous vegetables. It is also manufactured and concentrated for use in dietary supplements.

What foods contain DIM?

Cruciferous vegetables such as broccoli, Brussels sprouts, cabbage and cauliflower contain indole-3-carbinol, from which DIM can form during digestion.

Is DIM a detox supplement?

DIM is sometimes marketed for “detoxification,” but there is not sufficient scientific evidence to support broad detoxification claims.

Can DIM be used with tamoxifen?

DIM may interact with tamoxifen metabolism. A randomized clinical trial found reduced levels of tamoxifen metabolites, including endoxifen, in women taking DIM with tamoxifen. Anyone taking tamoxifen should discuss DIM with their oncologist or healthcare professional before use.

Can DIM affect birth-control pills?

Because DIM can affect hormone-related pathways and drug metabolism, people using hormonal contraceptives should consult a healthcare professional before using DIM.

Can pregnant or breastfeeding women take DIM?

DIM has potential hormonal effects, and safety during pregnancy and breastfeeding has not been adequately established. Memorial Sloan Kettering advises against DIM use during pregnancy, when planning pregnancy and while nursing.

Does DIM prevent cancer?

DIM has demonstrated interesting effects in laboratory and early clinical research, but there is not enough evidence to establish DIM as a cancer-prevention or cancer-treatment supplement.

What are possible side effects of DIM?

Clinical studies have generally reported tolerability at studied amounts, but nausea, headache and vomiting have been reported. Rare case reports have also described more serious adverse events.

Does DIM affect medications?

Potentially. DIM can influence enzymes and transport pathways involved in drug metabolism. Particular caution is warranted with hormone therapies, tamoxifen and medicines metabolized through relevant CYP450 or MDR1 pathways.
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